In order to obtain a stage coach mail contract, a new road must be built. A gang of outlaws try to prevent the building of the road.
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The arrival of the telegraph put Pony Express riders like John Blair and his pal Smoky out of work. A race will decide whether they or stageline owner Drake get the government mail contract.
It's 1876 and all the Indians are at peace except the Comanches lead by Black Cloud. When Black Cloud wipes out a town, only six soldiers are left and they head for the nearest fort. In the desert they are reinforced by members of a stagecoach and find some water at a deserted mission. Pinned down by Black Cloud they send an Indian boy who was Black Cloud's prisoner on to the fort while they try to bargain with Black Cloud whom they learn is without water.
Two down-on-their-luck former outlaws volunteer to be Texas Rangers and find themselves assigned to bring in an old friend, now a notorious outlaw.
Three cowboys, mistaken for members of an outlaw gang, are relentlessly pursued by a posse.
Hoppy is busy chasing stagecoach bandits who sing as they rob.
Stagecoach robbers take the money Hoppy was going to use to buy cattle so Hoppy, California and Lin go after them.